<p>Novel Albumin Nanoparticle Enhanced the Anti-Insulin-Resistant-Hepatoma Activity of Metformin</p>
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چکیده
منابع مشابه
Clonal variation in albumin messenger RNA activity in hepatoma cells.
The clonal variation in rate of albumin synthesis in hepatoma cells is described as a tool for the study of epigenetic control of differentiation. Previous studies have demonstrated that, from a population of hepatome cells, variant subclones can be readily isolated that produce albumin at different rates. Each clonal variant had a characteristic rate of albumin production, and the clones clust...
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heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...
15 صفحه اولInsulin negatively regulates albumin mRNA at the transcriptional and post-transcriptional level in rat hepatoma cells.
Treatment of cultured H4-II-E rat hepatoma cells with insulin causes a large decrease in cytoplasmic serum albumin mRNA. This effect is observed at low doses of insulin (ED50 = 2 pM), consistent with the effect being mediated by interaction of insulin with high affinity insulin receptors. The reduction in cytoplasmic albumin mRNA is first observed 8-12 h following insulin addition, and albumin ...
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Epidemiological evidence suggests that treatment with f l-blockers and diuretics increase the risk to develop diabetes. Prospective, randomized studies of antihypertensive drugs have demonstrated differences between different classes of drugs regarding effects on insulin sensitivity. Thus treatment with ,-blockers or diuretics is associated with impairment in insulin sensitivity, whereas most m...
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Experiments are described further indicating that 02-resistant photosynthesis observed in a tobacco (Nicotiana tabacum) mutant with enhanced catalase activity is associated with decreased photorespiration under conditions of high photorespiration relative to net photosynthesis. The effects on net photosynthesis of (a) increasing O2 concentrations from 1% to 42% at low CO2 (250 microliters CO2 p...
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ژورنال
عنوان ژورنال: International Journal of Nanomedicine
سال: 2020
ISSN: 1178-2013
DOI: 10.2147/ijn.s253094